PARKINSON’S DISEASE – THERAPY WITH STEM CELL
Researchers working seriously to come out with a viable and potential treatment for Parkinson’s have got a major breakthrough. There are fortunately, good enough advances and treatments in medical research to offer new hope to the people, who suffer from Parkinson’s disease. Stem cell therapy is one of such treatments to relieve the people suffering from Parkinson’s disease and help them to live better quality of life with optimum health. Now embryonic stem cells can be used to produce new dopamine cells and transplant them into the brain, where the cells are lost, leaving Parkinson.
Parkinson’s Disease stands as the second disease that most is most common neurodegenerative. This degenerative neurological disease affects primarily the motor system of the body. It affects 1 in 100 sixty plus aged people, approximately and at least seven million people in the world suffer from the Parkinson’s Disease.
Most of the Parkinson patients get the complications related to the dopamine neurons failure to perform the intended work properly. These neurons have the function to send the signals to the brain that have master control of the body and so the movements. Consequently, brain lets the muscles to move, according to the directions sent by the brain. In a nutshell, dopamine chemical in the brain helps regulation the emotional responses and movements. The dopamine neurons would no longer be enough quantity of dopamine and the function of the same is hindered, eventually, the person suffers and has troubles to move the muscles and perform the intended tasks.
Parkinson’s disease has no cure with traditional medication, such as drugs, but they can slow it down, though ease the symptoms. In certain patients, deep stimulation into brain can alleviate the Parkinson symptoms.
Treatment with Stem Cells
Human embryonic stem cells that can be precursor cells have the potential to transform into any cell within the body and stand now as a promising source for production of the new dopamine cells. However, it was difficult to harness, for this treatment. And a new breakthrough study completed from Lund University in Sweden proved that it is possible to produce a new dopamine cells generation from human embryonic stem cells and can behave just the same as native dopamine cells, when tested or rats, through transplantation into the brains. It is added by the study and research team that there can be unlimited supply from the stem cell source lines and the same opens the door to the clinical applications.
Parkinson’s disease can be treated with the stem cells, as the treatment is designed to focus and target the dopamine neurons and enable these neurons to produce afresh and function, as intended. Additionally, neural chemicals, known as cytokines that are capable to induce stem cells differentiation to the dopamine producing neurons, can be released by stem cells.
As reported from International Stem Cells Corporation, the first group’s fourth and last patient has successfully received the transplant, in a clinical stem cell transplants trial, in Parkinson’s disease. Further research is on its way to prepare for the following stage, where the higher number of cells can be received by the same patients. And no adverse events are recorded by the researchers among the four patients who had them transplanted with ISC-hpNSC neural stem cells, into their brains. The four clinical trials have proved that the stem cell therapy has enough potential for lost nerve cells regeneration and revolutionalize the way Parkinson can be treated.
The actual clinical treatment is very close and very soon, as the clinical trials show positive results with no adverse events.